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04 Jul
Antibacterial Substance Linked to Cancer Antibacterial Substance Linked to Cancer

Antibacterial Substance Linked to Cancer

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Researchers at the University of Massachusetts at Amherst recently announced that they had discovered a link between the antimicrobial ingredient triclosan, used in hand soaps and toothpastes as well as other products, and cancer.

Specifically, the research group determined that the substance could have a negative impact on colonic inflammation and colon cancer by changing gut microbiota, the microbes which reside in human intestines.

The study, published in Science Translational Medicine, indicates that short-time treatment with low-dose triclosan resulted in low-grade colonic inflammation, and pronounced disease development of colitis and colitis-associated colon cancer in mice, said Guodong Zhang, who authored the study, in a press release.

“These results, for the first time, suggest that triclosan could have adverse effects on gut health,” he noted.

The study also pointed out that triclosan ranks among the most commonly used antimicrobial ingredients and is present in over 2,000 consumer products. In fact, the authors said, a National Health and Nutrition Examination Survey indicated that triclosan was present in about 3 out of 4 urine samples of people tested in the United States, and it also ranks in the top ten pollutants found in American rivers.

“Because this compound is so widely used, our study suggests that there is an urgent need to further evaluate the impact of triclosan exposure on gut health in preparation for the potential establishment of further regulatory policies,” said Haixia Yang, a postdoctoral fellow in Zhang laboratory.

The research team also determined that feeding triclosan to mice cut down on the variety and altered the makeup of the gut microbiome, a result along the lines of what was observed in a human study overseen by others, said Zhang.

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Read 970 times Last modified on Thursday, 21 June 2018 08:54
Jim Lillie

Jim began writing for newspapers and designing for publishing companies at a time when both industries were just beginning to make the switch from manual to digital platforms. Jim lives in Boulder, Colorado with his teenage son.

Website: www.jimlillie.com
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