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The polio vaccine pretty much wiped the disease off the map in most areas of the world, but researchers are reintroducing it. This time, the disease is being used in the battle against cancer. A team of doctors have genetically engineered a version of polio that can be injected into a tumor to battle the toughest type of brain cancer.

Glioblastoma is notoriously resistant to cancer treatment, making it one of the deadliest types. Those who are diagnosed with glioblastoma often find that medical treatments are ineffective in prolonging its progression. By injecting an engineered polio virus into the tumor, researchers hope to put the disease’s paralysis effects to use in extending the lives of those who are diagnosed with glioblastoma.

Published in Our Blog
Wednesday, 08 November 2017 00:00

Suicide Molecule Could Be Key to Battling Cancer

As researchers work hard to find a cure for cancer, the best solution may be to cause cancer cells to self-destruct. Working with this concept, a team at Northwestern University believe RNA molecules they’ve dubbed “suicide molecules” are the key to battling cancerous tumors.

The molecules were originally developed to study gene function, but researchers found that when injected into a cancer cell, they trigger an ancient kill switch that prevents the disease from developing. The lead study author has been searching for molecules that provided this function for years.

Published in Our Blog
Saturday, 07 October 2017 00:00

T-Cell Therapy Could Be Key to Battling Cancer

In late August, the FDA approved tisagenlecleucel for treatment in relapsed or refractory B-cell precursor acute lymphoblastic leukemia. The approval was specific to children and young adults, but it’s considered an important first step in the eventual use of this type of therapy in other cancer incidents.

Also known as CAR T-Cell therapy, this treatment involves removing T cells from a patient and genetically modifying them so that when re-implanted, they attack B cells. The treatment attacks all B cells, not just the cancerous ones, but it is an improvement over traditional therapy for this type of leukemia. Currently, patients with B-cell precursor acute lymphoblastic leukemia undergo some combination of radiation, chemotherapy, targeted therapy, or a stem cell transplant, with long-term success rates extremely poor.

Published in Our Blog
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